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PREY VENG Cheap Greg Maddux Jersey , Cambodia, April 19 (Xinhua) -- A China-funded power transmission system was inaugurated here on Wednesday after three years' construction, officials said.


Cambodian Minister of Mines and Energy Suy Sem and Chinese Ambassador Xiong Bo jointly launched the 160-km project.


According to a report by Keo Rattanak, director-general of Cambodia's state-owned Electricite du Cambodge, the project included two substations and a 115-kilovolt line stretching from southern Kandal province to southeastern Prey Veng and Svay Rieng provinces.


""The line is capable of transmitting 150 megawatts (MW) electric power in its first phase, and its capacity will be doubled in the future,"" he said.


He added that the project was built by the China National Heavy Machinery Corporation at the cost of 75 million U.S. dollars which was a concessional loan from the Chinese government.


""This project is crucial to ensuring the supply of electric power with reliability Cheap Billy Williams Jersey , quality, stability and sustainability in these provinces,"" he said. ""Hundreds of thousands of people in the three provinces will get benefit from it.""


Suy Sem said the Southeast Asian country currently has 115-kilovolt and 230-kilovolt transmission lines in a total length of 1,525 km.


He added that the electric power supply available in 2016 was 2,008 MWs, including 1,592 MWs taken from hydropower plants Cheap Sammy Sosa Jersey , coal-fired power plants, oil-fueled power plants, and solar power plants, and 416 MWs imported from Vietnam, Thailand and Laos.


""The development of electric power sources and national grid is a key element for boosting economic development and reducing poverty,"" he said.


""The inauguration of the 115-kilovolt power transmission line today is another testament to the fruitful cooperation between Cambodia and China,"" the minister said.


Most of electric power sources and transmission lines in Cambodia have been developed by Chinese firms.


Ambassador Xiong said China is pleased to see the Chinese enterprises actively engaging in the development of electric power sources and national grid in Cambodia.


""We believe that these achievements will greatly contribute to economic growth and living conditions for the Cambodian people Cheap Mark Grace Jersey ,"" he said.


Meanwhile, Xiong said that under the ""Belt and Road"" initiative, China will continue to support Cambodia in all fields, especially in the development of connectivity infrastructure.

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SAN FRANCISCO, March 22 (Xinhua) -- Researchers have found a small molecule that was able to block the production of a specific protein involved in low-density lipoprotein (LDL) turnover by stalling only the ribosome that produces that protein.


Reported in the journal PLOS Biology, the discovery of the chemical compound, which halted the production of a small set of proteins while leaving general protein production untouched Cheap Kosuke Fukudome Jersey , suggests a new drug search strategy: find compounds that target undesired proteins before they are even made.


Many of today's therapies for cancer or heart disease are monoclonal antibodies that bind and disable proteins outside the cell. The immunotherapeutic checkpoint inhibitors block suppressor proteins, unleashing the immune system to attack cancer. But they aren't effective against all proteins, can't enter cells and must be delivered via injection.


Ribosomes are large, general-purpose molecular machines that translate genetic instructions in the form of messenger RNA into the proteins used to build cells, the enzymes in charge of cellular housekeeping, and the hormones that carry messages in and between cells. While antibiotics are known to stall the ribosome, they halt production of most proteins Cheap Joe Maddon Jersey , explained Jamie Cate, a University of California, Berkeley, professor of molecular and cell biology and of chemistry.


In the study by Cate and his colleagues at UC Berkeley and Pfizer Worldwide Research and Development, the small molecule, when delivered orally to rats, lowered LDL cholesterol levels Cheap Jake Arrieta Jersey , much the way statins do, though by a different mechanism: by lowering the production of the protein PCSK9, short for proprotein convertase subtilisin kexin 9. The chemical stalls the ribosome only when it's producing PCSK9 and a couple of dozen other proteins out of the tens of thousands of proteins the body produces, as shown by a relatively new technique called ribosomal profiling.


Knocking out PCSK9 is known to lower blood levels of LDL cholesterol, the so-called bad cholesterol, presumably lowering risk of cardiovascular disease.


""PCSK9 was just where we started. Now we can think about how to come up with other small molecules that hit proteins that nobody has been able to target before because, maybe Cheap Miguel Montero Jersey , they have a floppy part, or they don' t have a nook or cranny where you can bind a small molecule to inhibit them,"" Cate was quoted as saying in a news release from UC Berkeley. ""This research is saying, we may be able to just prevent the synthesis of the protein in the first place.""


Suspecting that the small molecule, a multi-ringed chlorinated compound, could serve as a template, like a key blank that can be machined to open a specific lock Cheap Anthony Rizzo Jersey , Cate said ""we now have this key blank that we can cut in a number of different ways to try to go after undruggable proteins in a number of different disease states.""


The molecule was discovered by Pfizer labs through live-cell screening for compounds that lower production of the protein PCSK9, which regulates the recycling of the LDL receptor.

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WASHINGTON, Aug. 9 (Xinhua) -- Admission policies employed bymost U.S. universities, in which skin color plays a major role,have put Asians at a disadvantage, a U.S. legal expert hassaid.


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